Use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or a friend to remind you or check in with you to be sure you are taking your medication. If you miss a dose of ziprasidone, take it as soon as you remember, unless it is closer to the time of your next dose.
Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed. Avoid drinking alcohol or using illegal drugs while you are taking ziprasidone. They may decrease the benefits e.
If an overdose occurs call your doctor or You may need urgent medical care. You may also contact the poison control center at Ziprasidone may increase the blood levels of a hormone called prolactin. Side effects of increased prolactin levels include females losing their period, production of breast milk and males losing their sex drive or possibly experiencing erectile problems. Long term months or years of elevated prolactin can lead to osteoporosis, or increased risk of bone fractures.
Some people may develop muscle related side effects while taking ziprasidone. Symptoms of EPS include restlessness, tremor, and stiffness. TD symptoms include slow or jerky movements that one cannot control, often starting in the mouth with tongue rolling or chewing movements. Temperature regulation: Impaired core body temperature regulation may occur; caution with strenuous exercise, heat exposure, and dehydration.
Second generation antipsychotics SGAs increase the risk of weight gain, high blood sugar, and high cholesterol. This is also known as metabolic syndrome. Your healthcare provider may ask you for a blood sample to check your cholesterol, blood sugar, and hemoglobin A1c a measure of blood sugar over time while you take this medication.
Information on healthy eating and adding exercise to decrease your chances of developing metabolic syndrome may be found at the following sites:. SGAs have been linked with higher risk of death, strokes, and transient ischemic attacks TIAs in elderly people with behavior problems due to dementia. All antipsychotics have been associated with the risk of sudden cardiac death due to an arrhythmia irregular heartbeat.
To minimize this risk, antipsychotic medications should be used in the smallest effective dose when the benefits outweigh the risks. Your doctor may order an EKG to monitor for irregular heartbeat.
Symptoms include confusion, fever, extreme muscle stiffness, and sweating. If any of these symptoms occur, contact your healthcare provider immediately.
All antipsychotics can cause sedation, dizziness, or orthostatic hypotension a drop in blood pressure when standing up from sitting or lying down. These side effects may lead to falls which could cause bone fractures or other injuries. This risk is higher for people with conditions or other medications that could worsen these effects. If falls or any of these symptoms occur, contact your healthcare provider. Severe skin reactions have been reported with ziprasidone.
Seek emergency treatment immediately if a severe skin reaction occurs. Tardive dyskinesia TD is a side effect that develops with prolonged use of antipsychotics. If you develop symptoms of TD, such as grimacing, sucking, and smacking of lips, or other movements that you cannot control, contact your healthcare provider immediately. All patients taking either first or second generation antipsychotics should have an Abnormal Involuntary Movement Scale AIMS completed regularly by their healthcare provider to monitor for TD.
Second generation antipsychotics SGAs increase the risk of diabetes, weight gain, high cholesterol, and high triglycerides. It is very important to tell your doctor how you feel things are going during the first few weeks after you start taking ziprasidone.
It will probably take several weeks to see big enough changes in your symptoms to decide if ziprasidone is the right medication for you. Antipsychotic treatment is generally needed lifelong for persons with schizophrenia. Your doctor can best discuss the duration of treatment you need based on your symptoms and illness. Last Updated: January This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists.
This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication.
Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein.
The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein. Search Close Menu. Sign In About Mental Illness. About Mental Illness Treatments. About Mental Illness Research.
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Your Journey Frontline Professionals. Get Involved Become a Fundraiser. Get Involved Awareness Events. Get Involved Share Your Story. Get Involved Partner with Us. Geodon injections are available in a single-dose vial to be reconstituted with sterile water for a total of 20 mg of ziprasidone. The recommended dosages of Geodon based on the condition are:. All listed dosages are according to the drug manufacturer. Check your prescription and talk to your doctor to make sure you are taking the right dose for you.
If you miss a dose of Geodon, you can take the dose when you remember. However, you should skip the missed dose if it's almost time for your next dose. You should never double up or take extra doses to make up for missed doses. All antipsychotic drugs will have side effects, ranging from mild to intolerable. Speak with your doctor in advance of treatment so that you are fully aware of the possible side.
Common side effects of Geodon use include:. Extrapyramidal symptoms , including tremors, shuffling, rocking, muscle rigidity, and involuntary movements dystonia , are common with all antipsychotic drugs.
Of the 15 antipsychotics currently approved for treatment, Geodon ranked eighth in the potential for extrapyramidal symptoms according to a study from Germany. Geodon may also trigger an allergic reaction in some people. In rare instances, this could lead to a potentially life-threatening, all-body allergy known as anaphylaxis.
Call or seek emergency care if you develop hives, rapid heart rate, breathing difficulty, lightheadedness, nausea or vomiting, and the swelling of the face, throat, or tongue after taking Geodon. Geodon is not approved for the treatment of dementia-related psychosis in elderly people. In fact, the FDA issued a black box warning advising patients and health professionals of the increased risk of death in this population of adults.
Most deaths were caused by either a cardiovascular event or an infection. The same warning has been issued with other antipsychotic drugs. There is also a slight risk roughly one in 4, that Geodon could trigger a potentially fatal change in heart rhythm, known as arrhythmia, leading to sudden death. As such, you should not take Geodon if you had a recent heart attack or have been diagnosed with severe heart failure, long QT syndrome, or certain heart rhythm disorders.
Call or seek emergency care if you faint or experience rapid heartbeats tachycardia or abnormal heart rhythms while taking Geodon. Geodon is contraindicated for use with any drug that affects the QT interval of the heart. These include:. Geodon should also not be used with any medication used to treat arrhythmia, including:. As such, carbamazepine may need to be substituted for another drug.
Because of its potential for inducing hypotension low blood pressure , Geodon may enhance the effects of certain drugs used to treat hypertension high blood pressure. One of the more exciting aspects of this novel antipsychotic drug is that, unlike earlier generation medications, Geodon is not associated with weight gain.
In an eight-week, head-to-head comparison study, Geodon performed just as well as Zyprexa olanzapine in alleviating symptoms of psychosis, including:. However, it did so with a mean weight gain of less than half a pound compared to a mean gain of almost 15 pounds with Zyprexa. Moreover, unlike Zyprexa, Geodon did not cause an increase in cholesterol and other blood lipids. These results suggest that Geodon is not only a "healthier" alternative but may decrease the risk of treatment termination due to weight gain.
As ziprasidone is primarily cleared from the body via the liver, Geodon may exacerbate any preexisting liver condition. This is especially true for people with cirrhosis in whom Geodon may increase liver impairment. If used, your doctor will need to monitor your liver enzymes to avoid liver toxicity and damage. Geodon may have negative effects during pregnancy.
Infants exposed to antipsychotics during the third trimester may experience extrapyramidal symptoms and withdrawal, and animal studies have shown that Geodon may carry an increased risk of adverse events.
However, the potential benefits of taking Geodon may outweigh the potential risks, so speak with your doctor if you are pregnant or planning to become pregnant. Geodon may travel through the breastmilk, and there is evidence that breastfeeding infants who are exposed to antipsychotics may experience some negative symptoms. You should discuss your options with your doctor before breastfeeding while taking this medication.
Before starting Geodon, advise your doctor if you:. Do not drink alcoholic beverages while taking Geodon as this can exacerbate symptoms of dizziness or fainting.
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